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ITX 3

3792 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3792/10
3792/50
ITX 3 | CAS No. 347323-96-0 | Rho GTPase Inhibitors
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Description: Selective TrioN RhoGEF activity inhibitor

Chemical Name: (E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one

Purity: ≥99%

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Biological Activity

ITX 3 is a selective inhibitor of TrioN RhoGEF activity. Inhibits TrioN-mediated GTP exchange on RhoG and Rac1, formation of TrioN-induced cellular structures in REF52 fibroblasts and NGF-mediated neurite outgrowth in PC12 cells in vitro.

Technical Data

M.Wt:
371.45
Formula:
C22H17N3OS
Solubility:
Soluble to 5 mM in DMSO
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
347323-96-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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