Chemical Name: (E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one
Biological ActivitySelective inhibitor of TrioN RhoGEF activity. Inhibits TrioN-mediated GTP exchange on RhoG and Rac1, formation of TrioN-induced cellular structures in REF52 fibroblasts and NGF-mediated neurite outgrowth in PC12 cells in vitro.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
A cell active chemical GEF inhibitor selectively targets the Trio/RhoG/Rac1 signaling pathway.
Bouquier et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for ITX 3
There are currently no reviews for this product. Be the first to review ITX 3 and earn rewards!
Have you used ITX 3?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image