IWP 4

Catalog # Availability Size / Price Qty
5214/10
5214/50
IWP 4 | CAS No. 686772-17-8 | beta-Catenin Inhibitors
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Description: Potent inhibitor of Wnt/β-catenin signaling

Chemical Name: N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3-(2-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]-acetamide

Purity: ≥98%

Product Details
Citations (2)
Supplemental Products
Reviews (1)

Biological Activity

IWP 4 is a potent inhibitor of Wnt/β-catenin signaling (IC50 = 25 nM). Has minimal effect on Notch and Hedgehog signaling pathways. Induces differentiation of cardiomyocytes from human ESCs and iPSCs.

Technical Data

M.Wt:
496.62
Formula:
C23H20N4O3S3
Solubility:
Soluble to 1 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
686772-17-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for IWP 4

The citations listed below are publications that use Tocris products. Selected citations for IWP 4 include:

2 Citations: Showing 1 - 2

FAQs

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would use again
By Anonymous on 05/10/2018
Application: Species: Human

colleague used for an experiment


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