Chemical Name: N-(5-Phenyl-2-pyridinyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]acetamide
Biological ActivityIWP L6 is a potent inhibitor of Porcupine (PORCN), a membrane-bound O-acyltransferase (MBOAT) (EC50 = 0.5 nM). Shown to inhibit Wnt-dependent processes such as tailfin regeneration and posterior axis formation in zebrafish; also reduces branching morphogenesis in cultured mouse embryonic kidneys.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
The development of highly potent inhibitors for Porcupine.
Wang et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for IWP L6
There are currently no reviews for this product. Be the first to review IWP L6 and earn rewards!
Have you used IWP L6?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image