JNJ 1013NC

Tocris Bioscience | Catalog # 8030

Negative control for the IRAK1 degrader JNJ 1013 (Cat. No. 8029)
Tocris Bioscience

Key Product Details

Description

Negative control for the IRAK1 degrader JNJ 1013 (Cat. No. 8029)
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Product Description

JNJ 1013NC is the negative control for the IRAK1 degrader, JNJ 1013 (Cat. No. 8029).

Product Specifications for JNJ 1013NC

Molecular Weight

878.06

Formula

C46H55N9O7S

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

N-(4-(4-(2-(((S)-1-((2S,4S)-4-Hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethoxy)piperidin-1-yl)-2-methoxyphenyl)-6-(1H-pyrazol-5-yl)picolinamide

CAS Number

2755075-91-1

PubChem ID

166627504

InChI Key

MHRNVFQJUUXQIG-LZJKKMSRSA-N

SMILES

O=C(C1=CC=CC(C2=NNC=C2)=N1)NC(C=C3)=C(OC)C=C3N(CC4)CCC4OCC(N[C@@H](C(C)(C)C)C(N5[C@@H](C[C@@H](C5)O)C(N[C@H](C6=CC=C(C7=C(C)N=CS7)C=C6)C)=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 87.81 100

Preparing Stock Solutions for JNJ 1013NC

The following data is based on the product molecular weight 878.06.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.14 mL 5.69 mL 11.39 mL
5 mM 0.23 mL 1.14 mL 2.28 mL
10 mM 0.11 mL 0.57 mL 1.14 mL
50 mM 0.02 mL 0.11 mL 0.23 mL

Calculators

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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Background References

References are publications that support the biological activity of the product.

Product Documents for JNJ 1013NC

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for JNJ 1013NC

For research use only

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