receptor antagonist; displays high affinity (Ki
= 4.5 nM) and is >1000-fold selective for H4
over other histamine receptors.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Sold with the permission of Ortho-McNeil-Janssen Pharmaceuticals, Inc.
The first potent and selective non-imidazole human histamine H4 receptor antagonists.
Jablanowski et al.
A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties.
Thurmond et al.
In vitro and in vivo characterization of A-940894: a potent histamine H4 receptor antagonist with anti-inflammatory properties.
Strakhova et al.