Chemical Name: (S)-5-(3-(1-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-2-oxo-7,10,13-trioxa-3-azahexadecan-16-yl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid trifluoroacetate
Biological ActivityJQ1-FITC is a fluorescent BET bromodomain probe. It binds with high affinity to BRD4(BD1) and BRD4(BD2) (KD,app = 6.5 nM and 5.8 nM, respectively). Suitable for use in TR-FRET. Excitation and emission maxima (λ) are 495 nm and 525 nm, respectively.
Optical Data for JQ1-FITC
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For batch specific data refer to the Certificate of Analysis.
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