Catalog Number: 5603
Chemical Name: (6R)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl ester
Biological Activity
Inactive control for (+)-JQ1 (Cat. No. 4499). Exhibits no significant interaction with BRD1-4 or a panel of other bromodomains.
Technical Data
  • M.Wt:
    456.99
  • Formula:
    C23H25ClN4O2S
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    1268524-71-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
This compound is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the (+)-JQ1 probe summary on the SGC website.
Other Product-Specific Information:
Background References
  1. Selective inhibition of BET bromodomains.
    Filippakopoulos et al.
    Nature, 2010;468:1067
Citations:

The citations listed below are publications that use Tocris products. Selected citations for (-)-JQ1 include:

1 Citations: Showing 1 - 1

  1. BET bromodomains regulate transforming growth factor-β-induced proliferation and cytokine release in asthmatic airway smooth muscle.
    Authors: Perry Et al.
    Scientific Reports 2015;290:9111

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