Chemical Name: (6R)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl ester
Biological Activity(-)-JQ1 is an inactive control for (+)-JQ1. Exhibits no significant interaction with BRD1-4 or a panel of other bromodomains.
Active Enantiomer also available.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Selective inhibition of BET bromodomains.
Filippakopoulos et al.
Citations for (-)-JQ1
The citations listed below are publications that use Tocris products. Selected citations for (-)-JQ1 include:
2 Citations: Showing 1 - 2
BET protein targeting suppresses the PD-1/PD-L1 pathway in triple-negative breast cancer and elicits anti-tumor immune response.
Authors: Andrieu Et al.
Cancer Lett 2019;465:45
BET bromodomains regulate transforming growth factor-β-induced proliferation and cytokine release in asthmatic airway smooth muscle.
Authors: Perry Et al.
Scientific Reports 2015;290:9111
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for (-)-JQ1
There are currently no reviews for this product. Be the first to review (-)-JQ1 and earn rewards!
Have you used (-)-JQ1?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image