Chemical Name: (6R)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl ester
Biological ActivityInactive control for (+)-JQ1. Exhibits no significant interaction with BRD1-4 or a panel of other bromodomains.
Active Enantiomer also available.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Selective inhibition of BET bromodomains.
Filippakopoulos et al.
Citation for (-)-JQ1
The citations listed below are publications that use Tocris products. Selected citations for (-)-JQ1 include:
1 Citation: Showing 1 - 1
BET bromodomains regulate transforming growth factor-β-induced proliferation and cytokine release in asthmatic airway smooth muscle.
Authors: Perry Et al.
Scientific Reports 2015;290:9111
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