(-)-JQ1

Catalog # Availability Size / Price Qty
5603/10
Cat.No. 5603 - (-)-JQ1 | C23H25ClN4O2S | CAS No. 1268524-71-5
1 Image
Description: Inactive control for (+)-JQ1 (Cat. No. 4499)

Chemical Name: (6R)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl ester

Purity: ≥98%

Product Details
Citations (1)
Reviews

Biological Activity

Inactive control for (+)-JQ1. Exhibits no significant interaction with BRD1-4 or a panel of other bromodomains.

Active Enantiomer also available.

Technical Data

M.Wt:
456.99
Formula:
C23H25ClN4O2S
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1268524-71-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Additional Information

Licensing Caveats:
This compound is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the (+)-JQ1 probe summary on the SGC website.
Other Product-Specific Information:

Background References

  1. Selective inhibition of BET bromodomains.
    Filippakopoulos et al.
    Nature, 2010;468:1067

Product Datasheets

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Citation for (-)-JQ1

The citations listed below are publications that use Tocris products. Selected citations for (-)-JQ1 include:

1 Citation: Showing 1 - 1

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