Chemical Name: 2-Chloro-N-[4-(4-methoxyphenyl)-2-thiazolyl]-N-(3-methoxypropyl)acetamide
Biological ActivityPotent and selective TRPA1 channel activator (EC50 = 65 nM); activates the TRPA1 channel by covalently and site-selectively binding to Cys621. Exhibits selectivity for TRPA1 over TRPV1, TRPV3, TRPV4, TRPM2, TRPM8, and TRPC5 channels (EC50 values are >1 μM).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
A Potent and Site-Selective Agonist of TRPA1.
Takaya J, Mio K, Shiraishi T et al.
J. Am. Chem. Soc.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for JT010
Average Rating: 5 (Based on 1 Review)
Have you used JT010?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
300 nM JT010 evoked Calcium responses in HEK293 cells transfected with recombinant TRPA1.