Catalog # Availability Size / Price Qty
JT010 | CAS No. 917562-33-5 | TRPA1 Activators
1 Image
Description: Potent and selective TRPA1 channel activator

Chemical Name: 2-Chloro-N-[4-(4-methoxyphenyl)-2-thiazolyl]-N-(3-methoxypropyl)acetamide

Product Details
Reviews (1)

Biological Activity

Potent and selective TRPA1 channel activator (EC50 = 0.65 nM); activates the TRPA1 channel by covalently and site-selectively binding to Cys621. Exhibits selectivity for TRPA1 over TRPV1, TRPV3, TRPV4, TRPM2, TRPM8, and TRPC5 channels (EC50 values are >1 μM).

Technical Data

Soluble to 100 mM in DMSO and to 50 mM in ethanol
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. A Potent and Site-Selective Agonist of TRPA1.
    Takaya J, Mio K, Shiraishi T et al.
    J. Am. Chem. Soc.

Product Datasheets

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.



No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for JT010

Average Rating: 5 (Based on 1 Review)

5 Star
4 Star
3 Star
2 Star
1 Star

Have you used JT010?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:

An excellent TRPA1 channel activator
By Zili Xie on 02/03/2019
Application: Species: Mouse

300 nM JT010 evoked Calcium responses in HEK293 cells transfected with recombinant TRPA1.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.