KA1/GRIK4/Glutamate Receptor KA1 Recombinant Protein Antigen

Novus Biologicals | Catalog # NBP2-62686PEP

Novus Biologicals
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Key Product Details

Source

E. coli

Applications

Antibody Competition
View all KA1/GRIK4 Proteins and Enzymes »

Product Specifications

Description

A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human GRIK4.

Source: E. coli

Amino Acid Sequence: LWTLRHSEATEVSVCQEMVTELRSIILCQDSIH

Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

Purity

>80% by SDS-PAGE and Coomassie blue staining

Predicted Molecular Mass

21 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Applications

Antibody Competition (10-100 molar excess)

Application Notes

This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP2-62686.

It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

Protein / Peptide Type

Recombinant Protein Antigen

Formulation, Preparation, and Storage

NBP2-62686PEP
Formulation PBS and 1M Urea, pH 7.4.
Preservative No Preservative
Concentration Please see the vial label for concentration. If unlisted please contact technical services.
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: KA1/GRIK4

The GRIK4 gene encodes a glutamate receptor KA-1 protein that is 956 amino acids long, 107 kDA and functions in the major excitatory neurotransmitter in the central nervous system (CNS) by activation of ligand-gated ion channels and G protein-coupled membrane receptors. GRIK4 participate in the neuroactive ligand-receptor interaction, glutamatergic synapse, activation of calcium-permeable kainate receptors, and transmission across chemical synapses. It is known to mainly interact with the GRIK2 gene. Researchers have investigated the role of GRIK4 in bipolar disorder, carcinoma, schizophrenia, parkinson's disease, neuronitis and medulloblastoma.

Long Name

Glutamate Receptor KA1

Alternate Names

EAA1, GluK4, GRIK4

Gene Symbol

GRIK4

Additional KA1/GRIK4 Products

Product Documents for KA1/GRIK4/Glutamate Receptor KA1 Recombinant Protein Antigen

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for KA1/GRIK4/Glutamate Receptor KA1 Recombinant Protein Antigen

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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