KF 38789

Catalog # Availability Size / Price Qty
2748/10
KF 38789 | CAS No. 257292-29-8 | Cell Adhesion Inhibitors
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Description: Selective inhibitor of P-selectin-mediated cell adhesion

Chemical Name: 3-[7-(2,4-Dimethoxyphenyl)-2,3,6,7-tetrahydro-1,4-thiazepin-5-yl]-4-hydroxy-6-methyl-2H-pyran-2-one

Purity: ≥97%

Product Details
Citations (2)
Supplemental Products
Reviews (1)

Biological Activity

Selective inhibitor of P-selectin-mediated cell adhesion (IC50 = 1.97 μM) that displays no effects on L-selectin- and E-selectin-mediated adhesion. Blocks P-selectin-mediated binding in vitro and leukocyte accumulation in vivo.

Technical Data

M.Wt:
375.44
Formula:
C19H21NO5S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥97%
Storage:
Desiccate at +4°C
CAS No:
257292-29-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for KF 38789

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We worked to determine the inhibitory effects of KF 38789 on P-selectin-mediated cell adhesion
By Meghan Bradshaw on 02/20/2019
Application: Species: Human

We worked to determine the inhibitory effects of KF 38789 on P-selectin-mediated cell adhesion.KF 38789 shows selective inhibition and works ideally.


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