Chemical Name: 3,5-Dibromo-N'-((2,5-dimethyl-1-(3-nitrophenyl)-1H-pyrrol-3-yl)methylene)-4-hydroxybenzohydrazide
Biological ActivityKinesin-1 modulator. Inhibits SKIP-KLC2 interaction, but promotes kinesin-1 function in controlling the organization of the microtubule network. Induces remodeling of the microtubule network and the formation of extensive microtubule-rich projections. Cell permeable.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
A small-molecule activator of kinesin-1 drives remodeling of the microtubule network.
Randall et al.
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