KIR3DL3/CD158z Antibody (CH21) - BSA Free

Novus Biologicals | Catalog # NBP3-21499

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # CH21

Format

BSA Free
View all KIR3DL3/CD158z Primary Antibodies »

Product Specifications

Immunogen

Human KIR3DL3/CD158z transfectants

Epitope

The mouse monoclonal antibody CH21 recognizes an extracellular epitope of human KIR3DL3/CD158z.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for KIR3DL3/CD158z Antibody (CH21) - BSA Free

Flow Cytometry: KIR3DL3/CD158z Antibody (CH21) - BSA Free [NBP3-21499] -

Flow cytometry surface staining pattern of KIR3DL3/CD158z transfected HEK-293 cells co-transfected with YFP coding plasmid using anti-human KIR3DL3/CD158z (CH21) purified antibody (concentration in sample 10 ug/ml, GAM APC).

Flow Cytometry: KIR3DL3/CD158z Antibody (CH21) - BSA Free [NBP3-21499] -

Flow cytometry surface staining patterns of non-transfected HEK-293 cells and HEK-293 cells transfected with KIR-family coding plasmids co-transfected with YFP coding plasmid using anti-human KIR3DL3/CD158z (CH21) purified antibody (concentration in sample 10 ug/ml, GAM APC).

Applications for KIR3DL3/CD158z Antibody (CH21) - BSA Free

Application
Recommended Usage

Flow Cytometry

3-12 ug/ml

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

Phosphate buffered saline (PBS), pH 7.4

Format

BSA Free

Preservative

15mM Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: KIR3DL3/CD158z

The KIR family is composed of at least 15 members expressed by natural killer (NK) cells and a subset of T cells in primates only. KIR proteins are named based on the number of extracellular Ig-like domains (KIR2D or KIR3D) and for whether the cytoplasmic domain is long (L), or short (S). Inhibitory KIR proteins possess long cytoplasmic tails with ITIM (inhibitory) domains, and several of these molecules bind HLA Class I molecules or target cells. Activating KIR proteins have short tails; their targets are less well-known. KIR2DL4 (CD158d) is unique in that it shows both inhibitory and activating characteristics.

Long Name

Killer Cell Immunoglobulin-like Receptor, Three Domain Long Cytoplasmic Tail, 3

Alternate Names

CD158z, KIR3DL7, KIR44, KIRC1

Gene Symbol

KIR3DL3

Additional KIR3DL3/CD158z Products

Product Documents for KIR3DL3/CD158z Antibody (CH21) - BSA Free

Certificate of Analysis

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Product Specific Notices for KIR3DL3/CD158z Antibody (CH21) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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