Q: I am interested in buying NBC1-18516. Have you tested it as a biologically active molecule to trigger cellular pathway?

A: At this time, we have only tested this protein for use in ELISA and PAGE. We would not be able to recommend this protein to trigger cellular pathways.

Recombinant Human KISS1 Protein

Novus Biologicals | Catalog # NBC1-18516

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Product Documents

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Source

E. coli

Applications

SDS-PAGE

View all Metastin/KiSS1 Proteins and Enzymes »

Product Specifications

Description

An un-tagged recombinant protein corresponding to the amino acids 1-120 of Human KISS1

Source: E.coli

Amino Acid Sequence: MEPLEKVASV GNSRPTGQQL ESLGLLAPGE QSLPCTERKP AATARLSRRG TSLSPPPESS GSPQQPGLSA PHSRQIPAPQ GAVLVQREKD LPNYNWNSFG LRFGKREAAP GNHGRSAGRG

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

12.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human KISS1 Protein

SDS-PAGE: Recombinant Human KISS1 Protein [NBC1-18516]

SDS-Page: Recombinant Human KISS1 Protein [NBC1-18516] - KISS1, 12.6 kDa (120 aa), confirmed by MALDI-TOF with a purity of 90% by SDS - PAGE

Formulation, Preparation, and Storage

NBC1-18516

Formulation	20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT, 10% glycerol
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Metastin/KiSS1

KiSS-1 metastasis-suppressor (KISS1) is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. Expression of KiSS1 has been localized to specific regions of the hypothalamus in many species and is regulated by gonadal steroids and across the estrous cycle. Recombinant KISS1 protein was expressed in E.coli and purified by using conventional chromatography techniques.

Long Name

KiSS-1 Metastasis-suppressor

Alternate Names

KiSS1, Kisspeptin-1

Gene Symbol

KISS1

Additional Metastin/KiSS1 Products

Product Documents for Recombinant Human KISS1 Protein

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Certificate of Analysis

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Product Specific Notices for Recombinant Human KISS1 Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Related Research Areas

Cancer Biomarkers

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