KJ Pyr 9

Key Product Details

Product Description

KJ Pyr 9 is a high affinity Myc inhibitor (K_d = 6.5 nM). Disrupts Myc-Max interaction. Inhibits Myc-dependent cancer cell line proliferation in vitro. Inhibits growth of MDA-MB-231 breast cancer cell xenografts in mice. Brain penetrant.

Product Specifications for KJ Pyr 9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for KJ Pyr 9

The following data is based on the product molecular weight 385.37.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.59 mL	12.97 mL	25.95 mL
5 mM	0.52 mL	2.59 mL	5.19 mL
10 mM	0.26 mL	1.30 mL	2.59 mL
50 mM	0.05 mL	0.26 mL	0.52 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

• Hart Inhibitor of MYC identified in a Kröhnke pyridine library. Proc.Natl.Acad.Sci.U.S.A. 2014 PMID: 25114221

Product Documents for KJ Pyr 9