KJ Pyr 9

Catalog # Availability Size / Price Qty
5306/50
5306/10
Cat.No. 5306 - KJ Pyr 9 | C22H15N3O4 | CAS No. 581073-80-5
1 Image
Description: High affinity Myc inhibitor

Chemical Name: 4-[2-(2-Furanyl)-6-(4-nitrophenyl)-4-pyridinyl]benzamide

Purity: ≥98%

Product Details
Citations (1)
Reviews

Biological Activity

High affinity Myc inhibitor (Kd = 6.5 nM). Disrupts Myc-Max interaction. Inhibits Myc-dependent cancer cell line proliferation in vitro. Inhibits growth of MDA-MB-231 breast cancer cell xenografts in mice. Brain penetrant.

Technical Data

M.Wt:
385.37
Formula:
C22H15N3O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
581073-80-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Background References

  1. Inhibitor of MYC identified in a Kröhnke pyridine library.
    Hart et al.
    Proc.Natl.Acad.Sci.U.S.A., 2014;111:12556

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Citation for KJ Pyr 9

The citations listed below are publications that use Tocris products. Selected citations for KJ Pyr 9 include:

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