KJ Pyr 9
Chemical Name: 4-[2-(2-Furanyl)-6-(4-nitrophenyl)-4-pyridinyl]benzamide
Biological ActivityHigh affinity Myc inhibitor (Kd = 6.5 nM). Disrupts Myc-Max interaction. Inhibits Myc-dependent cancer cell line proliferation in vitro. Inhibits growth of MDA-MB-231 breast cancer cell xenografts in mice. Brain penetrant.
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Inhibitor of MYC identified in a Kröhnke pyridine library.
Hart et al.
Citation for KJ Pyr 9
The citations listed below are publications that use Tocris products. Selected citations for KJ Pyr 9 include:
1 Citation: Showing 1 - 1
Downregulation of ribosome biogenesis during early forebrain development.
Authors: Chau Et al.
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