Catalog Number: 5306
Chemical Name: 4-[2-(2-Furanyl)-6-(4-nitrophenyl)-4-pyridinyl]benzamide
Biological Activity
High affinity Myc inhibitor (Kd = 6.5 nM). Disrupts Myc-Max interaction. Inhibits Myc-dependent cancer cell line proliferation in vitro. Inhibits growth of MDA-MB-231 breast cancer cell xenografts in mice. Brain penetrant.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
  • Storage:
    Store at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Inhibitor of MYC identified in a Kröhnke pyridine library.
    Hart et al.
    Proc.Natl.Acad.Sci.U.S.A., 2014;111:12556
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