KLD 12 New
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Description: Self-assembling peptide; forms hydrogel to support cell growth
Biological Activity
Self-assembling peptide that forms a hydrogel matrix to support growth of cells in the presence of an ionic solution. Enhances chondrogenic differentiation of bone marrow stromal cells (BMSCs).Technical Data
Formula:
C68H122N16O19
Sequence:
KLDLKLDLKLDL
(Modifications: Lys-1 = N-terminal Ac, Leu-12 = C-terminal amide)
Solubility:
Soluble to 0.50 mg/ml in water
Storage:
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
CAS No:
800379-47-9
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: implications for cartilage tissue repair.
Kisiday et al.
Proc.Natl.Acad.Sci.U.S.A., 2002;99:9996 -
Variants of self-assembling peptide, KLD-12 that show both rapid fracture healing and antimicrobial properties.
Tripathi et al.
Biomaterials., 2015;56:92
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