KRIBB11

Catalog # Availability Size / Price Qty
5480/10
5480/50
HSP90 Inhibitors Small Molecule
1 Image
Description: HSF1 inhibitor

Chemical Name: N2-1H-Indazol-5-yl-N6-methyl-3-nitro-2,6-pyridinediamine

Purity: ≥99%

Product Details
Reviews

Biological Activity

Heat shock factor (HSF) inhibitor (IC50 = 1.2 μM). Increases apoptosis in cancer cells treated with the HSP90 inhibitors Geldanamycin (Cat. No. 1368) and 17-AAG (Cat. No. 1515). Blocks downstream induction of HSP27 and HSP70. Inhibits tumor growth in vivo.

Technical Data

M.Wt:
284.27
Formula:
C13H12N6O2
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at -20°C
CAS No:
342639-96-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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