Potent, selective inhibitor of protein kinase A (Ki
= 60 nM). Has no effect on PKG or PKC (Ki
> 2 μ
M). Reversibly arrests human skin fibroblasts in the G1
Soluble to 50 mM in DMSO
Desiccate at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Effects of selective inhibition of protein kinase C, cyclic AMP-dependent protein kinase, and Ca(2+)-calmodulin-dependent protein kinase on neurite development in cultured rat hippocampal neurons.
Cabell et al.
Int.J.Dev. Neurosci., 1993;11:357
Multiple kinase arrest points in the G1 phase of nontransformed mammalian cells are absent in transformed cells.
Gadbois et al.
K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases.
Kase et al.
The citations listed below are publications that use Tocris products. Selected citations for KT 5720 include:
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