KYL

Catalog # Availability Size / Price Qty
5290/1
KYL
1 Image
Description: EphA4 kinase inhibitor; neuroprotective
Product Details
Citations (1)
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Biological Activity

EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM). Prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. Exhibits a long half life in cell culture media (8 and 12 hours in PC3 and C2C12 media respectively). Neuroprotective.

Technical Data

M.Wt:
1465.75
Formula:
C74H108N14O17
Sequence:
KYLPYWPVLSSL
Solubility:
Soluble to 2 mg/ml in water
Storage:
Store at -20°C
CAS No:
676657-00-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citation for KYL

The citations listed below are publications that use Tocris products. Selected citations for KYL include:

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FAQs

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