L 012 sodium salt
Chemical Name: 8-Amino-5-chloro-2,3-dihydro-7-phenyl-pyrido[3,4-d]pyridazine sodium salt
Biological ActivityL 012 sodium salt is a luminal-based chemiluminescent probe. Detects NAPDH oxidase-derived reactive oxygen and nitrogen species (ROS and RNS). Active in vitro and in vivo.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012.
Kielland et al.
Free Radic.Biol.Med., 2009;47:760
Noninvasive assessment of localized inflammatory responses.
Zhou et al.
Free Radic.Biol.Med., 2012;52:218
Evaluation of lophine derivatives as L-012 (luminol analog)-dependent chemiluminescence enhancers for measuring horseradish peroxidase and H2 O2.
Ichibangase et al.
Citation for L 012 sodium salt
The citations listed below are publications that use Tocris products. Selected citations for L 012 sodium salt include:
1 Citation: Showing 1 - 1
Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteolysis.
Authors: Mentrup Et al.
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