L-165,041

Catalog # Availability Size / Price Qty
1856/10
1856/50

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L-165,041 | CAS No. 79558-09-1 | PPAR delta Receptor Agonists
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Description: Potent PPARδ agonist

Chemical Name: [4-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy]acetic acid

Purity: ≥98%

Product Details
Citations (2)
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Reviews

Biological Activity

L-165,041 is a potent PPARδ agonist (Ki = 6 nM); displays > 100-fold selectivity for both mouse and human PPARδ receptors over other subtypes. Raises plasma cholesterol levels in vivo, in insulin-resistant db/db mice. Neuroprotective in models of cerebral infarction and Parkinson's disease.

Technical Data

M.Wt:
402.44
Formula:
C22H26O7
Solubility:
Soluble to 50 mM in 1eq. NaOH and to 100 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
79558-09-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for L-165,041

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