L-732,138

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Background References

1. Characterization of the interaction of N-acyl-L-tryptophan benzyl ester neurokinin antagonists with the human neurokinin-1 receptor.
   Cascieri et al.
   J.Biol.Chem., 1994;269:6587
2. Lipopolysaccharide enhances neurogenic plasma exudation in guinea-pig airways.
   Kuo et al.
   Br.J.Pharmacol., 1998;125:711
3. N-Acyl-L-tryptophan benzyl esters: potent substance P receptor antagonists.
   MacLeod et al.
   J.Med.Chem., 1993;36:2044
4. Identification of L-tryptophan derivatives with potent and selective antagonist activity at the NK₁ receptor.
   MacLeod et al.
   J.Med.Chem., 1994;37:1269

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