L-Ascorbic acid

Catalog # Availability Size / Price Qty
4055/50
Cat.No. 4055 - L-Ascorbic acid | C6H8O6 | CAS No. 50-81-7
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Description: Enhances the generation of iPSCs; increases reprogramming efficiency
Alternative Names: L-Ascorbate, Vitamin C

Chemical Name: 3-Oxo-L-gulofuranolactone

Purity: ≥99%

Product Details
Citations (4)
Reviews (1)

Biological Activity

Inhibitor of Cav3.2 channels (IC50 = 6.5 μM); displays no effect on Cav3.1 or Cav3.3 channels heterologously expressed in HEK 293 cells. Also enhances the generation of induced pluripotent stem cells (iPSCs) from mouse and human somatic cells by increasing reprogramming efficiency. Naturally occurring antioxidant.

Technical Data

M.Wt:
176.12
Formula:
C6H8O6
Solubility:
Soluble to 500 mM in water and to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
50-81-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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iPSC media
By Pinyuan Tian on 07/17/2018
Species: Human

Homemade media for iPSC culture containing L-Ascorbic Acid at a final concentration of 50 ug/ml gives consistent results. Image shows Mapx-5 cell line, containing collagen IV mutations from an Alport Syndrome patient.


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