Compounds for Induced Pluripotent Stem Cells: Products

Induced pluripotent stem (iPS) cells were first generated from fibroblasts by exogenously expressing four transcription factors: KLF4, c-Myc, Oct-4, and SOX2.

"Compounds for Induced Pluripotent Stem Cells" has 43 results in Products.
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SB 431542 

Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7

SB 431542 

SB 431542 synthesized to cGMP guidelines

CHIR 99021 

Highly selective GSK-3 inhibitor; acts as Wnt activator

3-Deazaneplanocin A hydrochloride 

EZH2 histone methyltransferase inhibitor

CHIR 99021 

CHIR 99021 synthesized to cGMP guidelines

A 83-01 

Selective inhibitor of TGF-βRI, ALK4 and ALK7

IWP 2 

PORCN inhibitor; inhibits Wnt processing and secretion

XAV 939 

Potent tankyrase inhibitor

LY 294002 hydrochloride 

Prototypical PI 3-kinase inhibitor; also inhibits other kinases

RepSox 

Potent and selective inhibitor of TGF-βRI

PD 0325901 

Potent inhibitor of MEK1/2

L-Ascorbic acid 

Enhances the generation of iPSCs; increases reprogramming efficiency

endo-IWR 1 

Wnt/β-catenin signaling inhibitor; axin stabilizer

Thiazovivin 

ROCK inhibitor; improves the efficiency of fibroblast reprogramming and induction of iPSCs

Cyclopamine 

Inhibitor of Hedgehog (Hh) signaling

Valproic acid, sodium salt 

Histone deacetylase inhibitor

Pifithrin-α hydrobromide 

p53 inhibitor. Also aryl hydrocarbon receptor agonist

CKI 7 dihydrochloride 

CK1 inhibitor

XAV 939 

XAV 939 synthesized to cGMP guidelines

TTNPB 

Retinoic acid analog; RAR agonist

Trichostatin A 

Potent histone deacetylase inhibitor

IWP 4 

Potent inhibitor of Wnt/β-catenin signaling

Sodium butyrate 

Histone deacetylase inhibitor

(±)-Bay K 8644 

CaV1.x activator

Tranylcypromine hydrochloride 

Irreversible inhibitor of LSD1; also inhibits MAO

IDE 1 

Induces definitive endoderm formation in mouse and human ESCs

KY 02111 

Inhibits canonical Wnt signaling. Promotes differentiation of human ESCs and iPSCs into cardiomyocytes

Polyamine Supplement x1000 (lyophilized) 

Media supplement to boost cell growth; used as component of CEPT cocktail to enhance stem cell viability

RepSox 

RepSox synthesized to Ancillary Material Grade

RG 108 

Non-nucleoside DNA methyltransferase inhibitor

BIX 01294 

GLP and G9a inhibitor

SR 3677 dihydrochloride 

Potent, selective Rho-kinase (ROCK) inhibitor

5-Azacytidine 

DNA methyltransferase inhibitor

A 83-01 

A 83-01 synthesized to Ancillary Material Grade

Kenpaullone 

GSK-3β inhibitor; also inhibits cdks

Pifithrin-μ 

Inhibitor of p53-mitochondrial binding

QS 11 

ARFGAP1 inhibitor; modulates Wnt/β-catenin signaling

PluriSln 1 

SCD-1 inhibitor

O4I2 

Oct3/4 inducer; induces expression of pluripotent-associated genes

T3 

T3 synthesized to Ancillary Material Grade

CEPT Cocktail Kit 

Cell culture supplement for improving stem cell survival

endo-IWR 1 

endo-IWR 1 synthesized to Ancillary Material Grade

L-Ascorbic acid 

L-Ascorbic acid synthesized to Ancillary Material Grade
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