Chemical Name: 3-(Methylamino)-L-alanine hydrochloride
Biological ActivityL-BMAA hydrochloride is a neurotoxic glutamate agonist originally isolated from Cycas circinalis. Implicated in the pathogenesis of amyotrophic lateral sclerosis-Parkinsonism-dementia complex of Guam (Guam ALS-PD).
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Neurotoxicity of β-N-methylamino-L-alanine (BMAA) and β-N-oxalylamino-L-alanine (BOAA) on cultured cortical neurons.
Weiss et al.
Brain Res., 1989;497:64
The preparation of L- and D-α-amino-β<-methylaminopropionic acids and the identification of the compound isolated from Cycas circinalis as the L-isomer.
Vega et al.
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