L-BMAA hydrochloride

Catalog # Availability Size / Price Qty
L-BMAA hydrochloride | CAS No. 16012-55-8 | Glutamate Receptor Compounds
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Description: Neurotoxic amino acid

Chemical Name: 3-(Methylamino)-L-alanine hydrochloride

Product Details

Biological Activity

L-BMAA hydrochloride is a neurotoxic glutamate agonist originally isolated from Cycas circinalis. Implicated in the pathogenesis of amyotrophic lateral sclerosis-Parkinsonism-dementia complex of Guam (Guam ALS-PD).

Technical Data

Soluble to 60 mM in water
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Neurotoxicity of β-N-methylamino-L-alanine (BMAA) and β-N-oxalylamino-L-alanine (BOAA) on cultured cortical neurons.
    Weiss et al.
    Brain Res., 1989;497:64
  2. The preparation of L- and D-α-amino-β<-methylaminopropionic acids and the identification of the compound isolated from Cycas circinalis as the L-isomer.
    Vega et al.
    Phytochemistry, 1968;7:1885

Product Datasheets

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