L-DOPA

Tocris Bioscience | Catalog # 3788

Dopamine precursor
Tocris Bioscience

Key Product Details

Description

Dopamine precursor

Alternative Names

Levodopa
View all Non-selective Dopamine Receptor Products »

Product Description

L-DOPA is an immediate precursor of dopamine, produced by tyrosine hydroxylase. Displays antiParkinsonian activity.

Product Specifications for L-DOPA

Molecular Weight

197.19

Formula

C9H11NO4

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

L-3,4-Dihydroxyphenylalanine

CAS Number

59-92-7

PubChem ID

6047

InChI Key

WTDRDQBEARUVNC-LURJTMIESA-N

SMILES

OC1=C(O)C=CC(C[C@H](N)C(O)=O)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 0.99 5
1eq. HCl 9.86 50

Preparing Stock Solutions for L-DOPA

The following data is based on the product molecular weight 197.19.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 10.14 mL 50.71 mL 101.43 mL
2.5 mM 2.03 mL 10.14 mL 20.29 mL
5 mM 1.01 mL 5.07 mL 10.14 mL
25 mM 0.20 mL 1.01 mL 2.03 mL

Calculators

Calculate the mass, volume, or concentration required for a solution.

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

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The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 37 publications citing the usage of this product.

  • Pisani and Shen Levodopa-induced dyskinesia and striatal signaling pathways. Proc.Natl.Acad.Sci.USA

Product Documents for L-DOPA

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for L-DOPA

For research use only

⚠ WARNING: This product can expose you to chemicals including Levodopa, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

Customer Reviews for L-DOPA (1)

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  • Very stable compound
    Name: Luiz Alexandre Magno
    Species: Mouse
    Assay Type: In Vivo
    Verified Customer | Posted 10/26/2018
    I have used L-DOPA to increase dopamine in mouse brain. There was an increase in dopamine levels in the striatum of animals treated with 4 injections of L-DOPA.
    L-DOPA 3788

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