L-NIL hydrochloride
Chemical Name: N6-(1-Iminoethyl)-L-lysine hydrochloride
Biological Activity
L-NIL hydrochloride is a selective inhibitor of inducible nitric oxide synthase (IC50 = 3.3 μM).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase.
Connor et al.
Eur.J.Pharmacol., 1995;273:15 -
L-N6-(1-Iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase.
Moore et al.
J.Med.Chem., 1994;37:3886
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Citations for L-NIL hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for L-NIL hydrochloride include:
4 Citations: Showing 1 - 4
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Hypoxia inducible factor signaling modulates susceptibility to mycobacterial infection via a nitric oxide dependent mechanism.
Authors: Elks Et al.
PLoS Pathog 2013;9:e1003789
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Peripheral effects of mor. and expression of μ-opioid receptors in the dorsal root ganglia during neuropathic pain: nitric oxide signaling.
Authors: Hervera Et al.
Mol Pain 2011;7:25
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The role of nitric oxide in the local antiallodynic and antihyperalgesic effects and expression of delta-opioid and cannabinoid-2 receptors during neuropathic pain in mice.
Authors: Hervera Et al.
J Pharmacol Exp Ther 2010;334:887
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Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway.
Authors: Pais Et al.
Mar Drugs 2008;5:43
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