Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-88411

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunocytochemistry/ Immunofluorescence

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Latent TGF-beta bp2/LTBP-2 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: ERSPNLRRSSAAGEGTLARAQPPAPQSPPAPQSPPAGTLSGLSQTHPSQQHVGLSRTVRLHPTATASSQLSSNALPPGPGLEQRDGTQQAVPLEHPSSPWGLNLTEKIKKIKIVFTPTICKQTCARGHCANSCERG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free

Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free Immunocytochemistry/ Immunofluorescence: Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free [NBP1-88411]

Immunocytochemistry/ Immunofluorescence: Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free [NBP1-88411]

Staining of human cell line U-2 OS shows localization to nucleus.
Latent TGF-beta bp2/LTBP-2 Antibody

Immunohistochemistry-Paraffin: Latent TGF-beta bp2/LTBP-2 Antibody [NBP1-88411] -

Immunohistochemistry-Paraffin: Latent TGF-beta bp2/LTBP-2 Antibody [NBP1-88411] -Staining of human placenta shows moderate positivity in extracellular space in trophoblastic cells.
Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free Immunohistochemistry-Paraffin: Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free [NBP1-88411]

Immunohistochemistry-Paraffin: Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free [NBP1-88411]

Staining of human cerebral cortex shows no positivity in neurons as expected.
Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free Immunohistochemistry-Paraffin: Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free [NBP1-88411]

Immunohistochemistry-Paraffin: Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free [NBP1-88411]

Staining of human skin shows no positivity in squamous epithelial cells as expected.
Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free Immunohistochemistry-Paraffin: Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free [NBP1-88411]

Immunohistochemistry-Paraffin: Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free [NBP1-88411]

Staining of human placenta shows moderate positivity in extracellular space in trophoblastic cells.
Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free Immunohistochemistry-Paraffin: Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free [NBP1-88411]

Immunohistochemistry-Paraffin: Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free [NBP1-88411]

Staining of human lung shows strong positivity in extracellular space in pneumocytes.

Applications for Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Latent TGF-beta bp2/LTBP-2

LTBP2, also known as latent-transforming growth factor beta-binding protein 2, is a 195 kDa, 1,821 amino acid protein that is involved in assembly and organization of cellular structure as a member of the latent transforming growth factor=beta binding protein (LTBP) family. Current research is being conducted to study the effect of the protein on diseases and disorders such as fibrosis, primary congenital glaucoma type 3D, carcinoma, hepatitis, melanoma, corneal edema, Weill-Marchesani Syndrome, and pancreatitis. The protein interacts in elastic fiber formation, paxillin interaction, mitochondrial apoptosis, extracellular matrix organization, and molecular mechanisms of cancer pathways with other proteins including FYN, FBLN5, and ABL1.

Alternate Names

Latent TGFbeta bp2, LTBP-2, LTBP2

Gene Symbol

LTBP2

Additional Latent TGF-beta bp2/LTBP-2 Products

Product Documents for Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Latent TGF-beta bp2/LTBP-2 Antibody - BSA Free

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Protocols

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