Reversible inhibitor of actin assembly; blocks actin adenine nucleotide exchange. Complexes with actin in vitro
and interacts with actin monomers only, unlike cytochalasins. Prevents actin repolymerization into filaments and disrupts the actin cytoskeleton.
Soluble to 10 mM in DMSO
Store at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Actin-latrunculin A structure and function.
Yarmola et al.
Latrunculin alters the actin-monomer subunit interface to prevent polymerization.
Morton et al.
Nat.Cell Biol., 2000;2:376
On the chemistry of latrunculins A and B.
Blasberger et al.
The citations listed below are publications that use Tocris products. Selected citations for Latrunculin A include:
Showing Results 1 - 5 of 5