Latrunculin A

Tocris Bioscience | Catalog # 3973

Inhibitor of actin assembly and polymerization
Tocris Bioscience

Key Product Details

Description

Inhibitor of actin assembly and polymerization
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Product Description

Latrunculin A is a reversible inhibitor of actin assembly; blocks actin adenine nucleotide exchange. Complexes with actin in vitro and interacts with actin monomers only, unlike cytochalasins. Prevents actin repolymerization into filaments and disrupts the actin cytoskeleton.

Product Specifications for Latrunculin A

Molecular Weight

421.55

Formula

C22H31NO5S

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

4-[(1R,4Z,8E,10Z,12S,15R, 17R)-17-Hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl)-2-thiazolidinone

CAS Number

76343-93-6

PubChem ID

445420

InChI Key

DDVBPZROPPMBLW-IZGXTMSKSA-N

SMILES

C[C@@H](CC[C@]2([H])C[C@@](C[C@](O)([C@]3([H])CSC(N3)=O)O2)([H])O1)\C=C/C=C/CC/C(C)=C\C1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 116 publications citing the usage of this product.

Product Documents for Latrunculin A

Certificate of Analysis

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Product Specific Notices for Latrunculin A

For research use only

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