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Laurdan

Catalog #: 7275 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7275/10
Laurdan | CAS No. 74515-25-6 | Fluorescent Lipids Probes and Cell Membrane Stains
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Description: Polarity sensitive lipid membrane fluorescent probe; used for imaging lipid rafts

Chemical Name: 1-[6-(Dimethylamino)-2-naphthalenyl]-1-dodecanone

Purity: ≥95%

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Biological Activity

Laurdan is a polarity sensitive fluorescent probe for imaging lipid rafts in membranes (also known as lipid microdomains). It is suitable for use with generalized polarization (GP) imaging and scanning fluorescence correlation spectroscopy (FCS). Laurdan can be used to image lipids in live and fixed cells as well as in whole tissues with multiphoton microscopy. Laurdan has emission maxima of 440 nm and 490 nm in gel and liquid phase membranes, respectively.

Optical Data for Laurdan

Laurdan Dye Spectra
λabs 366 nm
λem 497 nm
Extinction Coefficient (ε) 19500 M-1cm-1
Quantum Yield (φ) 0.61
Application Polarity sensitive fluorescent probe for lipid raft and cell membrane investigations
Alternative For C-Laurdan, Di-4-ANEPPDHQ

Technical Data

M.Wt:
353.55
Formula:
C24H35NO
Solubility:
Soluble to 20 mM in DMF
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
74515-25-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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