LCLAT1 Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-14187

Novus Biologicals
Discontinued Product
NBP2-14187 has been discontinued. View all LCLAT1 products.

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: ICLKASLKGVPGFGWAMQAAAYIFIHRKWKDDKSHFEDMIDYFCDIHEPLQLLIFPEGTDLTENSKSRSNAFAEKNGLQKYEYV

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (89%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for LCLAT1 Antibody - BSA Free

Immunohistochemistry-Paraffin: LCLAT1 Antibody [NBP2-14187]

Immunohistochemistry-Paraffin: LCLAT1 Antibody [NBP2-14187]

Immunohistochemistry-Paraffin: LCLAT1 Antibody [NBP2-14187] - Staining of human heart muscle shows cytoplasmic positivity in myocytes.
LCLAT1 Antibody - BSA Free

LCLAT1 Antibody [NBP2-14187] -

Staining of human small intestine shows weak granular cytoplasmic positivity in glandular cells.
LCLAT1 Antibody - BSA Free

LCLAT1 Antibody [NBP2-14187] -

Staining of human lung shows weak granular cytoplasmic positivity in subset of pneumocytes.
LCLAT1 Antibody - BSA Free

LCLAT1 Antibody [NBP2-14187] -

Staining of human skeletal muscle shows no positivity in myocytes as expected.

Applications for LCLAT1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LCLAT1

Acyl-CoA:lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) andlysophosphatidylglycerol acyltransferase (LPGAT) activities. Recognizes both monolysocardiolipin and dilysocardiolipinas substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme forcardiolipin, a major membrane polyglycerophospholipid. Converts lysophosphatidic acid (LPA) into phosphatidic acid(PA) with a relatively low activity. Required for establishment of the hematopoietic and endothelial lineages

Alternate Names

1-acylglycerol-3-phosphate O-acyltransferase 8, 1-AGPAT 8, Acyl-CoA:lysocardiolipin acyltransferase 1, AGPAT8lysocardiolipin acyltransferase, ALCAT11AGPAT8, EC 2.3.1.-, EC 2.3.1.51, FLJ37965, HSRG1849, LYCAT, lysocardiolipin acyltransferase 1, UNQ1849,1-AGP acyltransferase 8

Gene Symbol

LCLAT1

Additional LCLAT1 Products

Product Documents for LCLAT1 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for LCLAT1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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