Chemical Name: 2,4-Dichloro-N-[[[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]amino]carbonyl]benzamide
Biological ActivityLDN 193188 is an inhibitor of phosphatidylcholine transfer protein (PC-TP). Regulates hepatic glucose metabolism. Also promotes insulin-independent phosphorylation of key insulin signaling molecules.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
Genetic ablation or chemical inhibition of phosphatidylcholine transfer protein attenuates diet-induced hepatic glucose production.
Shishova et al.
Small-molecule inhibitors of phosphatidylcholine transfer protein/StarD2 identified by high-throughput screening.
Wagle et al.
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