Catalog Number: 5631
Chemical Name: 2,4-Dichloro-N-[[[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]amino]carbonyl]benzamide
Biological Activity
Inhibitor of phosphatidylcholine transfer protein (PC-TP). Regulates hepatic glucose metabolism. Also promotes insulin-independent phosphorylation of key insulin signaling molecules.
Technical Data
  • M.Wt:
    494.35
  • Formula:
    C20H17Cl2N5O4S
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    1267610-30-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Small-molecule inhibitors of phosphatidylcholine transfer protein/StarD2 identified by high-throughput screening.
    Wagle et al.
    Anal.Biochem., 2008;383:85
  2. Genetic ablation or chemical inhibition of phosphatidylcholine transfer protein attenuates diet-induced hepatic glucose production.
    Shishova et al.
    Hepatology, 2011;54:664

Have you used LDN 193188?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

Feedback

Customer Information