LDN 193188

Key Product Details

Product Description

LDN 193188 is an inhibitor of phosphatidylcholine transfer protein (PC-TP). Regulates hepatic glucose metabolism. Also promotes insulin-independent phosphorylation of key insulin signaling molecules.

Product Specifications for LDN 193188

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for LDN 193188

The following data is based on the product molecular weight 494.35.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.02 mL	10.11 mL	20.23 mL
5 mM	0.40 mL	2.02 mL	4.05 mL
10 mM	0.20 mL	1.01 mL	2.02 mL
50 mM	0.04 mL	0.20 mL	0.40 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Wagle Small-molecule inhibitors of phosphatidylcholine transfer protein/StarD2 identified by high-throughput screening. Anal.Biochem. 2008 PMID: 18762160
• Shishova Genetic ablation or chemical inhibition of phosphatidylcholine transfer protein attenuates diet-induced hepatic glucose production. Hepatology 2011 PMID: 21538437

Product Documents for LDN 193188