LDN 209929 dihydrochloride

Key Product Details

Product Description

LDN 209929 dihydrochloride is a potent and selective haspin kinase inhibitor (IC₅₀ = 55 nM). Displays 180-fold selectivity over DYRK2.

Product Specifications for LDN 209929 dihydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for LDN 209929 dihydrochloride

The following data is based on the product molecular weight 405.77.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.46 mL	12.32 mL	24.64 mL
5 mM	0.49 mL	2.46 mL	4.93 mL
10 mM	0.25 mL	1.23 mL	2.46 mL
50 mM	0.05 mL	0.25 mL	0.49 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Cuny Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors. Bioorg.Med.Chem.Lett. 2010 PMID: 20836251

Product Documents for LDN 209929 dihydrochloride