LDV FITC
1 Image
Description: Fluorescent ligand for α4β1 (VLA-4)
Purity: ≥95%
Biological Activity
LDV FITC is a fluorescent ligand that binds to the α4β1 integrin (VLA-4) with high affinity (Kd values are 0.3 nM and 12 nM for binding to U937 cells in the presence and absence of Mn2+ respectively). Used to detect VLA-4 affinity and conformational changes.Technical Data
M.Wt:
1368.54
Formula:
C69H81N11O17S
Sequence:
LDVPAAK (Modifications: Leu-1 N-2-[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl-, Lys-6 N-FITC conjugate)
Solubility:
Soluble to 1 mg/ml in PBS (pH 7.4)
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
1207610-07-8
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Real time analysis of the affinity regulation of alpha 4-integrin. The physiologically activated receptor is intermediate in affinity between resting and Mn2+ or antibody activation.
Chigaev et al.
J.Biol.Chem., 2001;276:48670 -
Conformational mAb as a tool for integrin ligand discovery.
Njus et al.
Assay Drug Dev.Technol., 2009;7:507 -
FRET detection of cellular α4-integrin conformational activation.
Chigaev et al.
Biophys.J., 2003;85:3951
Product Datasheets
Or select another batch:
Reconstitution Calculator
Molarity Calculator
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Peptide FAQsVersaClone cDNA Plasmids
Reviews for LDV FITC
There are currently no reviews for this product. Be the first to review LDV FITC and earn rewards!
Have you used LDV FITC?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Tocris Bioscience is the leading supplier of novel and exclusive
tools for
life science research with over 30 years' experience in the
industry.
Tocris is a Bio-Techne brand.
