LDV FITC

Tocris Bioscience | Catalog # 4577

Fluorescent ligand for α4β1 (VLA-4)
Tocris Bioscience

Key Product Details

Description

Fluorescent ligand for α4β1 (VLA-4)
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Product Description

LDV FITC is a fluorescent ligand that binds to the α4β1 integrin (VLA-4) with high affinity (Kd values are 0.3 nM and 12 nM for binding to U937 cells in the presence and absence of Mn2+ respectively). Used to detect VLA-4 affinity and conformational changes. Wavelengths are compatible with use as an acceptor dye in TR-FRET assays, together with the CoraFluor™ 1 (Cat. No. 7920) TR-FRET donor.

Optical Data

Application TR-FRET, Confocal Microscopy

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Product Specifications for LDV FITC

Molecular Weight

1368.54

Formula

C69H81N11O17S

Storage

Store at -20°C

Purity

≥90% (HPLC)

CAS Number

1207610-07-8

PubChem ID

91826076

InChI Key

PAAUNHNWVWSJKI-CBRXRBRLSA-N

SMILES

CC(C)C[C@H](NC(=O)Cc1ccc(NC(=O)Nc2ccccc2C)cc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCNC(=S)Nc1ccc(C(O)=O)c(c1)-c1c-2ccc(=O)cc-2oc2cc(O)ccc12)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solubility Soluble to 1mg/ml in PBS (pH 7.4)

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 9 publications citing the usage of this product.

Product Documents for LDV FITC

Certificate of Analysis

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Product Specific Notices for LDV FITC

For research use only

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