[Leu⁵]-Enkephalin

Name: [Leu 5 ]-Enkephalin
Brand: Tocris Bioscience
SKU: 1889
Price: 152 USD
Availability: InStock

Tocris Bioscience | Catalog # 1889

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Citations (8)

Product Documents

Endogenous opioid agonist peptide

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Endogenous opioid agonist peptide

Alternative Names

ICI 114740,Dynorphin-(1-5),YGGFL

View all Miscellaneous/Non-selective Opioid Agonists »

Product Description

[Leu⁵]-Enkephalin is an endogenous opioid agonist peptide; inhibits electrically stimulated contractions in mouse vas deferens (IC₅₀ = 11.4 nM). Short-acting in vivo.

Product Specifications for [Leu⁵]-Enkephalin

Molecular Weight

555.63

Formula

C₂₈H₃₇N₅O₇

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

58822-25-6

PubChem ID

461776

InChI Key

URLZCHNOLZSCCA-VABKMULXSA-N

SMILES

[H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 1mg/ml in water

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 8 publications citing the usage of this product.

Law and Loh ³H-Leu⁵-enkephalin specific binding to synaptic membrane - comparison with ³H-dihydromorphine and ³H-naloxone. Res.Commun.Chem.Pathol.Pharmacol. 1978 PMID: 705021
Meunier Binding of Leu⁵-enkephalin and Met⁵-enkephalin to a particulate fraction from rat cerebrum. FEBS Lett. 1977 PMID: 862920
DiMaio Synthesis and pharmacological characterization in vitro of cyclic enkephalin analogues: effect of conformational constraints on opiate receptor selectivity. J.Med.Chem. 1982 PMID: 6296388

Product Documents for [Leu⁵]-Enkephalin

Certificate of Analysis

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Product Specific Notices for [Leu⁵]-Enkephalin

For research use only

Citations for [Leu⁵]-Enkephalin

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