Catalog Number: 1889
Alternate Names: ICI 114740, Dynorphin-(1-5), YGGFL
Biological Activity
Endogenous opioid agonist peptide; inhibits electrically stimulated contractions in mouse vas deferens (IC50 = 11.4 nM). Short-acting in vivo.
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:
  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. 3H-Leu5-enkephalin specific binding to synaptic membrane - comparison with 3H-dihydromorphine and 3H-naloxone.
    Law and Loh
    Res.Commun.Chem.Pathol.Pharmacol., 1978;21:409
  2. Synthesis and pharmacological characterization in vitro of cyclic enkephalin analogues: effect of conformational constraints on opiate receptor selectivity.
    DiMaio et al.
    J.Med.Chem., 1982;25:1432
  3. Binding of Leu5-enkephalin and Met5-enkephalin to a particulate fraction from rat cerebrum.
    Meunier et al.
    FEBS Lett., 1977;77:209

The citations listed below are publications that use Tocris products. Selected citations for [Leu5]-Enkephalin include:

1 Citations: Showing 1 - 1

  1. N-glycan-mediated quality control in the endoplasmic reticulum is required for the expression of correctly folded delta-opioid receptors at the cell surface.
    Authors: Markkanen and Petäjä-Repo
    J Biol Chem 2008;283:29086

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