Leupeptin hemisulfate (CAS 103476-89-7): R&D Systems
Catalog Number: 1167
Biological Activity
Reversible inhibitor of trypsin-like and cysteine proteases such as calpain. Shown to inhibit activation-induced programmed cell death.
Technical Data
  • M.Wt:
    475.04
  • Formula:
    C20H38N6O4.½H2SO4
  • Sequence:
    LLR

    (Modifications: Leu-1 = N-terminal Ac, Arg-3 = Arginal)

  • Solubility:
    Soluble to 10 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    103476-89-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Inhibition of activation-induced programmed cell death and restoration of defective immune responses of HIV+ donors by cysteine protease inhibitors.
    Sarin et al.
    J.Immunol., 1994;153:862
  2. Developing selective inhibitors of calpain.
    Wang
    TiPS, 1990;11:139
  3. Cell-penetrating inhibitors of calpain.
    Mehdi
    TiBS, 1991;16:150
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Leupeptin hemisulfate include:

1 Citations: Showing 1 - 1

  1. Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity.
    Authors: Haller Et al.
    J Pharmacol Exp Ther 2015;10:2269

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