Biological Activity RNA binding protein Lin28 inhibitor (IC50 = 8 μM). Blocks binding of Lin28 to let-7 pre-micro RNA. Inhibits stemness and induces differentiation of murine ESCs. Inhibits growth of tumor cell lines and tumor-sphere formation in vitro. Also bromodomain inhibitor.
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Store at +4°C
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