Recombinant Human LINGO-1 His Protein

Name: Recombinant Human LINGO-1 His Protein
Brand: Novus Biologicals
SKU: NBP2-52016
Price: 349 USD
Availability: InStock

Novus Biologicals | Catalog # NBP2-52016

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Source

E. coli

Tag

His

Applications

SDS-PAGE

View all LINGO-1 Proteins and Enzymes »

Product Specifications

Description

A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 241-337 of Human LINGO-1

Source: E.coli

Amino Acid Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSLKVL EISHWPYLDT MTPNCLYGLN LTSLSITHCN LTAVPYLAVR HLVYLRFLNL SYNPISTIEG SMLHELLRLQ EIQLVGGQLA VVEPYAFRGL NYL

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

15.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Application Notes

Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human LINGO-1 His Protein

SDS-PAGE: Recombinant Human LINGO-1 His Protein [NBP2-52016]

SDS-Page: Recombinant Human LINGO-1 Protein [NBP2-52016]

Formulation, Preparation, and Storage

NBP2-52016

Formulation	20 mM Tris-HCl buffer (pH 8.0), 10% glycerol
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LINGO-1

Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible forsome inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator ofoligodentrocyte differentiation and axonal myelination

Long Name

Leucine-rich Repeat And Ig Domain Containing Nogo Receptor-Interacting Protein 1

Alternate Names

LERN1, LINGO1, LRRN6A

Gene Symbol

LINGO1

Additional LINGO-1 Products

Product Documents for Recombinant Human LINGO-1 His Protein

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Certificate of Analysis

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Product Specific Notices for Recombinant Human LINGO-1 His Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Related Research Areas

Glial Lineage Markers

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