Lofepramine

Catalog # Availability Size / Price Qty
2545/10
2545/50
Lofepramine | CAS No. 23047-25-8 | 5-HT Transporter Inhibitors
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Description: 5-HT and NA reuptake inhibitor (SNRI)
Alternative Names: Lopramine, Leo 640

Chemical Name: 1-(4-Chlorophenyl)-2-[[3-(10,11-dihydro-5H-dibenz(Z)[b,f]azepin-5-yl)propyl]methylamino]ethanone

Purity: ≥99%

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Biological Activity

Serotonin and noradrenalin re-uptake inhibitor (SNRI) that is metabolized to desipramine. Produces inhibition of liver tryptophan pyrollase activity in vitro and displays antidepressant properties in vivo.

Technical Data

M.Wt:
418.97
Formula:
C26H27N2OCl
Solubility:
Soluble to 75 mM in DMSO and to 10 mM in ethanol
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
23047-25-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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