Chemical Name: 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepine-2-one
Biological ActivityLigand at the GABAA receptor benzodiazepine modulatory site. Anxiolytic, anticonvulsant and sedative/hypnotic agent.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Tolerance to the sedative effect of lorazepam correlates with a diminution in cortical release and affinity for glutamate.
Bonavita et al.
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