Lorazepam

Catalog # Availability Size / Price Qty
3087/50
Cat.No. 3087 - Lorazepam | C15H10Cl2N2O2 | CAS No. 846-49-1
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Description: Ligand at benzodiazepine site

Chemical Name: 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepine-2-one

Product Details
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Biological Activity

Ligand at the GABAA receptor benzodiazepine modulatory site. Anxiolytic, anticonvulsant and sedative/hypnotic agent.

Technical Data

M.Wt:
321.16
Formula:
C15H10Cl2N2O2
Solubility:
Soluble to 100 mM in DMSO and to 40 mM in ethanol
Storage:
Store at RT
CAS No:
846-49-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

Background References

  1. Tolerance to the sedative effect of lorazepam correlates with a diminution in cortical release and affinity for glutamate.
    Bonavita et al.
    Neuropharmacol., 2002;42:619

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