Catalog Number: 3087
Chemical Name: 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepine-2-one
Biological Activity
Ligand at the GABAA receptor benzodiazepine modulatory site. Anxiolytic, anticonvulsant and sedative/hypnotic agent.
Technical Data
  • M.Wt:
    321.16
  • Formula:
    C15H10Cl2N2O2
  • Solubility:
    Soluble to 100 mM in DMSO and to 40 mM in ethanol
  • Storage:
    Store at RT
  • CAS No:
    846-49-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Tolerance to the sedative effect of lorazepam correlates with a diminution in cortical release and affinity for glutamate.
    Bonavita et al.
    Neuropharmacol., 2002;42:619

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