Catalog Number: 5835
Chemical Name: 2-(4-Morpholinyl)-8-(1-naphthalenyl)-4H-1,3-benzoxazin-4-one
Biological Activity
PI 3-kinase δ inhibitor (IC50 values are 0.64 and 5.0 μM for PI-3Kδ and PI3Kβ, respectively). Exhibits anticancer activity in a renal cancer cell line.
Technical Data
  • M.Wt:
    358.39
  • Formula:
    C22H18N2O3
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at +4°C
  • CAS No:
    1879887-94-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Synthesis, structure elucidation, DNA-PK and PI3K and anti-cancer activity of 8- and 6-aryl-substituted-1-3-benzoxazines.
    Morrison et al.
    Eur.J.Med.Chem., 2016;110:326
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