Chemical Name: 2-[2-(5-Bromo-1H-indol-3-yl)ethyl]-3-[3-(1-methylethoxy)phenyl]-4-(3H)-quinazoline
Biological ActivityLY 225910 is a potent CCK2 receptor antagonist (IC50 = 9.3 nM for inhibition of 125I-labeled CCK-8 sulfate binding at mouse brain membranes).
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Tocris products are intended for laboratory research use only, unless stated otherwise.
The influence of guanyl nucleotide on agonist and antagonist affinity at guinea-pig CCK-B / gastrin receptors: binding studies using [3H]PD140376.
Suman-Chauhan et al.
Quinazolinone cholecystokinin receptor ligands.
Yu et al.
Citations for LY 225910
The citations listed below are publications that use Tocris products. Selected citations for LY 225910 include:
3 Citations: Showing 1 - 3
Phencyclidine-induced social withdrawal results from deficient stimulation of cannabinoid CB1 receptors: implications for schizophrenia.
Authors: Seillier Et al.
Cholecystokinin inhibits endocannabinoid-sensitive hippocampal IPSPs and stimulates others.
Authors: Karson Et al.
J Card Fail 2008;54:117
Cortical sources of CRF, NKB, and CCK and their effects on pyramidal cells in the neocortex.
Authors: Gallopin Et al.
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