Chemical Name: [3S-(3α,4aα,6β,8aα)]-Decahydro-6-(phosphonomethyl)-3-isoquinolinecarboxylic acid)
Biological ActivityCompetitive NMDA receptor antagonist.
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Competitive and non-competitive NMDA antagonists induce similar limbic degeneration.
Competitive NMDA-receptor antagonists, LY 235959 and LY 233053, enhance the protective efficacy of various antiepileptic drugs against maximal electroshock-induced seizures in mice.
Borowicz et al.
Citations for LY 235959
The citations listed below are publications that use Tocris products. Selected citations for LY 235959 include:
2 Citations: Showing 1 - 2
Habenular α5 nicotinic receptor subunit signalling controls nicotine intake.
Authors: Fowler Et al.
NMDA receptors regulate nicotine-enhanced brain reward function and intravenous nicotine self-administration: role of the ventral tegmental area and central nucleus of the amygdala.
Authors: Kenny Et al.
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