Chemical Name: [3S-(3α,4aα,6β,8aα)]-Decahydro-6-(phosphonomethyl)-3-isoquinolinecarboxylic acid)
Biological ActivityLY 235959 is a competitive NMDA receptor antagonist.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Competitive and non-competitive NMDA antagonists induce similar limbic degeneration.
Competitive NMDA-receptor antagonists, LY 235959 and LY 233053, enhance the protective efficacy of various antiepileptic drugs against maximal electroshock-induced seizures in mice.
Borowicz et al.
Citations for LY 235959
The citations listed below are publications that use Tocris products. Selected citations for LY 235959 include:
2 Citations: Showing 1 - 2
Habenular α5 nicotinic receptor subunit signalling controls nicotine intake.
Authors: Fowler Et al.
NMDA receptors regulate nicotine-enhanced brain reward function and intravenous nicotine self-administration: role of the ventral tegmental area and central nucleus of the amygdala.
Authors: Kenny Et al.
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