Catalog Number: 3078
Chemical Name: 1-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-one hydrochloride
Biological Activity
5-HT1D-preferring receptor antagonist (EC50 = 31 nM). Displays no activity on 5-HT transport.
Technical Data
  • M.Wt:
    430.94
  • Formula:
    C24H27FN2O2.HCl
  • Solubility:
    Soluble to 10 mM in water and to 100 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Desiccate at RT
  • CAS No:
    192927-92-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold under license from Eli Lilly and company
Background References
  1. The role of the 5-HT1D receptor as a presynaptic autoreceptor in the guinea pig.
    Pullar et al.
    Eur.J.Pharmacol., 2004;493:85
Citations:

The citations listed below are publications that use Tocris products. Selected citations for LY 310762 hydrochloride include:

1 Citations: Showing 1 - 1

  1. Evaluation of AaDOP2 receptor antagonists reveals antidepressants and antipsychotics as novel lead molecules for control of the yellow fever mosquito, Aedes aegypti.
    Authors: Conley Et al.
    Pain 2015;352:53

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