LY 320135

Catalog # Availability Size / Price Qty
2387/10
2387/50
LY 320135 | CAS No. 176977-56-3 | Cannabinoid R1 / CB1 Inverse Agonists
1 Image
Description: Selective CB1 inverse agonist

Chemical Name: 4-[[6-Methoxy-2-(4-methoxyphenyl)-3-benzofuranyl]carbonyl]benzonitrile

Purity: ≥98%

Product Details
Citations (4)
Supplemental Products
Reviews

Biological Activity

Potent CB1 receptor antagonist/inverse agonist (Ki = 141 nM) with greater than 70-fold selectivity over CB2 receptors (Ki > 10 μM). Structurally dissimilar from SR 141716A and AM 251. Shows weak binding to both 5-HT2 (Ki = 6.4 μM) and muscarinic receptors (Ki = 2.1 μM).

Technical Data

M.Wt:
383.4
Formula:
C24H17NO4
Solubility:
Soluble to 30 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
176977-56-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citations for LY 320135

The citations listed below are publications that use Tocris products. Selected citations for LY 320135 include:

4 Citations: Showing 1 - 4

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for LY 320135

There are currently no reviews for this product. Be the first to review LY 320135 and earn rewards!

Have you used LY 320135?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.