LY 334370 hydrochloride

  ( 1 citations )    
Product Datasheet
Catalog Number:3079
Chemical Name:4-Fluoro-N-[3-(1-methyl-4-piperidinyl)-1H-indol-5-yl]benzamide hydrochloride
Product Details
Citations (1)
Supplemental Products
Reviews
Biological Activity
Selective 5-HT1F receptor agonist (Ki values are 1.87, 16.4, > 100 (IC50), 176, 189, 281, 1280, 1530, 1550, > 3000 (IC50) and 3250 nM for 5-HT1F, 5-HT1A, 5-HT4, 5-HT1E, 5-HT1B, 5-HT1D, 5-HT2B, 5-HT2A, 5-HT7, 5-HT6 and 5-HT2C receptors respectively). Displays antimigraine effects.
Technical Data
  • M.Wt:
    387.88
  • Formula:
    C21H22FN3O.HCl
  • Solubility:
    Soluble to 25 mM in water with gentle warming and to 25 mM in DMSO with gentle warming
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    199673-74-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold under license from Eli Lilly and company
Product Datasheets
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for LY 334370 hydrochloride include:

1 Citations: Showing 1 - 1

  1. Agonism of the 5-hydroxytryptamine 1F receptor promotes mitochondrial biogenesis and recovery from acute kidney injury.
    Authors: Garrett Et al.
    J Pharmacol Exp Ther  2014;350:257

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