Chemical Name: (1S,2S,4R,5R,6S)-rel-2-Amino-4-methylbicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Biological ActivitySelective metabotropic glutamate ligand for mGlu2 and mGlu3 receptors (Ki values are 0.165 μM and 0.302 μM respectively). Acts as an agonist at mGlu2 and antagonist at mGlu3. Analog of LY 354740 (Cat. No. 3246).
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Citations for (±)-LY 395756
The citations listed below are publications that use Tocris products. Selected citations for (±)-LY 395756 include:
2 Citations: Showing 1 - 2
Metabotropic glutamate receptor 2 inhibits thalamically-driven glutamate and DA release in the dorsal striatum.
Group II metabotropic glutamate receptor agonist LY379268 regulates AMPA receptor trafficking in prefrontal cortical neurons.
Authors: Wang Et al.
Mol Pain 2013;8:e61787
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