LY 354740

Catalog # Availability Size / Price Qty
3246/10
3246/50
LY 354740 | CAS No. 176199-48-7 | Group II mGluR Agonists
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Description: Potent and highly selective group II mGlu agonist

Chemical Name: (1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid

Purity: ≥98%

Product Details
Citations (5)
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Biological Activity

Highly selective and potent agonist of group II mGlu receptors (EC50 values are 5.1 and 24.3 nM at mGlu2 and mGlu3 receptors respectively and > 100000 nM at mGlu4, mGlu7, mGlu1a and mGlu5a receptors). Displays antianxiety and antiaddictive activity in vivo. Orally and systemically active.

Technical Data

M.Wt:
185.18
Formula:
C8H11NO4
Solubility:
Soluble to 100 mM in 1eq. NaOH
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
176199-48-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for LY 354740

The citations listed below are publications that use Tocris products. Selected citations for LY 354740 include:

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