Chemical Name: 2,3-Dichloro-α-methylbenzylamine hydrochloride
Biological ActivityLY 78335 is a high affinity inhibitor of phenylethanolamine-N-methyltransferase (PNMT) (Ki = 0.09 μM in vitro). Suppresses the release of growth hormone in an in vivo rat model.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Inhibition of phenylethanolamine N-methyltransferase by benzylamines. 2. In vitro and in vivo studies with 2,3-dichloro-α-methylbenzylamine.
Fuller et al.
Regulation of episodic GH secretion by the central epinephrine system.
Terry et al.
Synthesis and evaluation of 3-substituted analogues of 1,2,3,4-tetrahydroisoquinoline as inhibitors of phenylethanolamine N-methyltransferase.
Grunewald et al.
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