Lyn peptide inhibitor

   
Product Datasheet
Catalog Number:2265
Chemical Name:
Product Details
Reviews
Biological Activity
Cell-permeable inhibitor of Lyn-dependent effects of the IL-5 receptor. Blocks binding of Lyn tyrosine kinase to βc subunit of IL-3/GM-CSF/IL-5 receptors, blocking Lyn activation. Inhibits IL-5 receptor-mediated eosinophil differentiation and survival in vitro. Inhibits airway eosinophilic inflammation in mouse model of asthma.
Technical Data
  • M.Wt:
    2370.91
  • Formula:
    C115H184N30O24
  • Sequence:
    YGYRLRRKWEEKIPNP

    (Modifications: Tyr-1 = Octadecanoyl-Tyr, Pro-16 = C-terminal amide)

  • Solubility:
    Soluble to 10 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    222018-18-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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