[Lys⁵,MeLeu⁹,Nle¹⁰]-NKA(4-10)

Name: [Lys 5 ,MeLeu 9 ,Nle 10 ]-NKA(4-10)
Brand: Tocris Bioscience
SKU: 3228

Tocris Bioscience | Catalog # 3228

Submit a review

Product Documents

Selective NK2 agonist

Discontinued Product

3228 has been discontinued. View all NK2 Receptor Agonists products.

Technical Data
Reviews

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Selective NK2 agonist

View all NK2 Receptor Agonists »

Product Description

Highy selective and potent NK₂ receptor agonist (IC₅₀ = 6.1 nM). Induces contraction of the rat fundus and bladder (EC₅₀ values are 117 and 10 nM respectively).

Product Specifications for [Lys⁵,MeLeu⁹,Nle¹⁰]-NKA(4-10)

Molecular Weight

804.00

Formula

C₃₉H₆₅N₉O₉

Storage

Desiccate at -20°C

CAS Number

137565-28-7

PubChem ID

10417908

InChI Key

FIBMQAYBIOYAKI-HLYNNXGTSA-N

SMILES

[H]N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](CCCC)C(N)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 1mg/ml in water

Calculators

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background References

References are publications that support the biological activity of the product.

Matuszek An investigation of tachykinin NK₂ receptor subtypes in the rat. Eur.J.Pharmacol. 1998 PMID: 9718274
Burcher Tachykinin NK₂ receptor and functional mechanisms in human colon: changes with indomet. and in diverticular disease and ulcerative colitis. J.Pharmacol.Exp.Ther. 2008 PMID: 17959748
Chassaing Selective agonists of NK-2 binding sites highly active on rat portal vein (NK-3 bioassay). Neuropeptides 1991 PMID: 1658676

Product Documents for [Lys⁵,MeLeu⁹,Nle¹⁰]-NKA(4-10)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for [Lys⁵,MeLeu⁹,Nle¹⁰]-NKA(4-10)

For research use only

Customer Reviews

There are currently no reviews for this product. Be the first to review [Lys⁵,MeLeu⁹,Nle¹⁰]-NKA(4-10) and earn rewards!

Have you used [Lys⁵,MeLeu⁹,Nle¹⁰]-NKA(4-10)?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 for a review with an image

$10/€7/£6/$10CAN/¥1110 for a review without an image